method for the preparation of a medicine with effect on the cerebral blood flow.

摘要

1480836 Compositions containing xanthine derivatives HOECHST AG 28 June 1974 [11 July 1973] 28866/74 Addition to 1417323 Heading A5B [Also in Division C2] Therapeutic compositions for improving the cerebral blood flow comprise compounds of formula or their physiologically acceptable acid addition salts, wherein one of R 1 , R 2 , R 3 is # or (#-1) C 4-8 hydroxyalkyl, and of the others, R 1 and R 3 are each H or C 1-12 alkyl and R 2 is C 1-12 alkyl, provided that at least one of R 1 , R 2 and R 3 contains one less than 5 carbon atoms, but excluding those compounds where either (a) R 1 = R 2 = Me and R 3 is HO(CH 2 ) 5 -, or (b) one of R 1 and R 3 is unbranched (#-1) C 5-8 hydroxyalkyl and the other of R 1 and R 3 , and R 2 , are Me. The compositions may be administered orally, parenterally or rectally, and may contain a further active ingredient such as a vitamin.