PHARMACEUTICAL COMPOSITION CONTAINING A GLYCYRREHETINIC ACID DERIVATIVE AND AN ANTACID FOR THE TREATMENT OF GASTRITIS

摘要

1401360 Pharmaceutical compositions BIOREX LABORATORIES LTD 29 Nov 1973 [18 Dec 1972] 58355/72 Heading A5B Pharmaceutical compositions for use in the treatment of gastritis in dosage unit form comprise 1-100 mg of at least one non-ulcerogenic, anti-inflammatory active derivative of glycyrrhetinic acid (selected from the esters, hemiesters and hemiester salts thereof e.g. the disodium salt of glycyrrhetininc acid hemisuccinate, the salts of glycyrrhetinic acid with non-toxic organic bases; the salts of glycyrrhetinic acid and its hemiesters with bismuth, zinc or a metal of Group IIA, IIIA or VIII of the Periodic Table; and the amides of glycyrrhetininc acid and of acylated glycyrrhetininc acid), in admixture with 1-70% by weight, referred to the total weight of the composition, of at least one antacid, non-toxic aluminium compound (such as aluminium hydroxide, aluminium magnesium silicate, aluminium phosphate, or dihydroxyaluminium aminoacetate). The antacid aluminium compound may be partially replaced by other known antacid compounds e.g. calcium carbonate, magnesium carbonate, magnesium hydroxide, magnesium trisilicate or sodium bicarbonate. The composition may be administered orally in the form of a tablet.