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method for preparation of 3 - hydroxy - 3 - cefe nestor - sulfoxiden.
method for preparation of 3 - hydroxy - 3 - cefe nestor - sulfoxiden.
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机译:制备3-羟基-3-cefe嵌套-亚砜的方法。
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摘要
7-Acylamido-3-exomethylenecepham ester sulfoxides are reacted with ozone to provide the corresponding 3-hydroxy-3-cephem ester sulfoxides, intermediates for 3-methoxy and 3-halo substituted cephalosporin antibiotics; e.g., p-nitrobenzyl 7-phenoxyacetamido-3-exomethylenecepham-4-carboxylate-1-oxide provides the corresponding 3-hydroxy-3-cephem ester sulfoxide.
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