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4-(Trimethoxycinnamoyl) piperazin-1-ylacetamides - for treating peripheral, coronary and cerebral circulatory insufficiency, and hypertension
4-(Trimethoxycinnamoyl) piperazin-1-ylacetamides - for treating peripheral, coronary and cerebral circulatory insufficiency, and hypertension
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机译:4-(三甲氧基肉桂酰基)哌嗪-1-基乙酰胺-用于治疗外周,冠状动脉和脑循环功能不全和高血压
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摘要
4, 5-Trimethoxycinnamoyl)piperazin-1-ylacetamides of formula (I) are new: (where is piperidino, heptamethyleneimino or 1,2,3,4-tetrahydroisoquinoleino; or R1 is 1-4C alkyl and R2 is dimethoxyphenylethyl). I(R1=Me; R2=3, 4-dimethoxyphenylethyl). is specif. claimed. Cpds. (I) are prepd. by condensn. of the corresp. acid with the amine using butyl chloroformate in presence of NEt3 in THF.
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