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Copolymers based on N-substituted acrylamides, N-substituted methacrylamides and N,N-disubstituted acrylamides and the method of their manufacturing

机译:基于N-取代的丙烯酰胺,N-取代的甲基丙烯酰胺和N,N-二取代的丙烯酰胺的共聚物及其制造方法

摘要

The invention relates to copolymers based on N-substituted acrylamides, N-substituted methacrylamides and N,N-disubstituted acrylamides and to a method for their manufacturing, which copolymers are prepared under conditions when the phase separation takes place. The resulting copolymer contains reactive groups and serves as the intermediate for preparation of biologically active compounds (enzymes, hormones, drugs, etc.) bonded to the polymer. The procedure according to the invention enables to prepare porous polymers suitable as separation barriers (membranes) or column packings for gel or affinity chromatography, if the polymerization is carried out in the presence of a divinyl component.
机译:本发明涉及基于N-取代的丙烯酰胺,N-取代的甲基丙烯酰胺和N,N-二取代的丙烯酰胺的共聚物及其制造方法,该共聚物在发生相分离的条件下制备。所得的共聚物含有反应性基团,并用作制备与聚合物键合的生物活性化合物(酶,激素,药物等)的中间体。如果聚合在二乙烯基组分的存在下进行,则根据本发明的方法能够制备适合作为凝胶或亲和色谱法的分离屏障(膜)或柱填料的多孔聚合物。

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