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6'-N-ALKYL-AND 6',6'-DI-N-ALKYL DERIVATIVES OF FORTIMICINS A AND B
6'-N-ALKYL-AND 6',6'-DI-N-ALKYL DERIVATIVES OF FORTIMICINS A AND B
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机译:A和B的6'-N-烷基和6',6'-DI-N-烷基衍生物
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摘要
Novel fortimicin antibiotics represented by the formula IMAGE wherein R1 is loweralkyl, R2 is hydrogen or loweralkyl and R3 is selected from the group consisting of hydrogen, acyl, hydroxyacyl, aminoacyl, N-monoloweralkylaminoacyl, N,N-diloweralkylaminoacyl, hydroxy-substituted aminoacyl or an aminoacid residue, loweralkyl, hydroxyloweralkyl, aminoloweralkyl, N-monoloweralkylaminoloweralkyl, N,N-diloweralkylaminoloweralkyl or hydroxy-substituted aminoloweralkyl; and the pharmaceutically acceptable salts thereof, intermediates useful in their preparation, compositions employing the compounds and methods of using the compounds.
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