首页> 外国专利> 2 - (4 - cyano - piperanzino) - 4 - amino - 6.7 - dimethoxy - chinazolin and its use for the production of 2 - 4 - (2 - furoyl) piperazine o - 4 - amino - 6.7 - dimethoxychinazolin

2 - (4 - cyano - piperanzino) - 4 - amino - 6.7 - dimethoxy - chinazolin and its use for the production of 2 - 4 - (2 - furoyl) piperazine o - 4 - amino - 6.7 - dimethoxychinazolin

机译:2-(4-氰基-哌嗪子)-4-氨基-6.7-二甲氧基-中国唑啉及其在生产2-[4-(2-呋喃酰基)哌嗪邻]-4-氨基-6.7-二甲氧基中国唑啉中的用途

摘要

Certain 2-(4-aroylpiperazin-1-yl)-4-amino-6,7-dimethoxyquinazolines are prepared by a novel process wherein certain 2-(4-substituted-piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline intermediates wherein said substituent is cyano, certain carbon-oxygen double bond containing groups or certain carbon-nitrogen double bond containing groups, are reacted with certain metalloaryl compounds followed by hydrolysis. The products are known hypotensive agents. Certain of the process intermediates are novel compounds.
机译:某些2-(4-芳酰基哌嗪-1-基)-4-氨基-6,7-二甲氧基喹唑啉是通过新方法制备的,其中某些2-(4-取代-哌嗪-1-基)-4-氨基-6,使所述取代基为氰基,某些含碳氧双键的基团或某些含碳氮双键的基团的7-二甲氧基喹唑啉中间体与某些金属芳基化合物反应,然后水解。该产品是已知的降压药。某些方法中间体是新型化合物。

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