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MOLECULAR COORDINATION COMPLEXES COMPRISING CELLULOSE POLYMERS AND CONTROLLED RELEASE COMPOSITIONS CONTAINING THEM
MOLECULAR COORDINATION COMPLEXES COMPRISING CELLULOSE POLYMERS AND CONTROLLED RELEASE COMPOSITIONS CONTAINING THEM
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机译:包含纤维素聚合物和包含它们的可控制释放成分的分子配位化合物
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摘要
Molecular coordination complexes are formed between a cellulose polymer and a non-polar solid aliphatic alcohol containing 8 to 18 carbon atoms optionally substituted with an aliphatic group containing 8 to 18 carbon atoms by solvating the polymer with a volatile polar solvent and reacting the solvated cellulose polymer directly with the aliphatic alcohol, preferably as a melt. The resulting composition may be dried. This constitutes the complex. The composition has utility as a matrix in controlled release formulations since it has a uniform porosity which may be varied.
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