Antigen composition comprising a synthetic adjuvant, method of administration thereof and use of the adjuvant to stimulate antigenic responses

摘要

An antigen composition such as tetanus toxoid or polyomyelitis vaccine having an improved efficacy over the plain antigen comprises at least one bacterial or viral antigenic species and at least one adjuvant in an amount effective to enhance the antigenic response of the antigenic species; the adjuvant is an ester of a long chain alcohol containing 10 to 22 carbon atoms and an amino acid, for example octadecyl tyrosine.