Process for the separation of 2,4-dinitro-6-t-butyl-3- methylanisole, referred to as musk ambrette, from the crude synthesis mixtures in which it is present

摘要

The invention relates to a process for the separation of 2,4- dinitro-6- t-butyl-3-methylanisole, referred to as musk ambrette, from the crude mixtures in which it is present, which are obtained by nitrating 6-t- butyl-3-methylanisole.PPAccording to the invention, an amount of water representing from 5 to 40% by weight of the nitrating mixture used in the synthesis is introduced onto the crude synthesis mixture in a first addition, the pure musk ambrette obtained is collected and several small amounts of water, representing from 1 to 15% by weight of the said nitrating mixture used, are then introduced, the precipitated product being collected between each addition. The process makes it possible to collect, in a pure form and without the use of an organic extraction solvent, about three quarters of the musk ambrette present in the crude synthesis mixture.