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Hexahydro-1-arylspiro(3H-oxazolo(3,4-A)pyridine-3,4'-piperidene) antidepressants, pharmaceutical compositions thereof and method of use thereof
Hexahydro-1-arylspiro(3H-oxazolo(3,4-A)pyridine-3,4'-piperidene) antidepressants, pharmaceutical compositions thereof and method of use thereof
Compounds of the formula ##STR1## where R.sub.1 is hydrogen, lower alkyl containing one to three carbon atoms, cycloalkyl lower alkyl containing four to seven carbon atoms, or benzyl; and R.sub.2 is hydrogen, halogen, alkoxy containing one to three carbon atoms, trifluoromethyl; and pharmaceutically acceptable acid addition salts thereof are useful as anti-depressants.
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机译:式中R 1是氢,含1至3个碳原子的低级烷基,含4至7个碳原子的环烷基低级烷基或苄基的化合物; R 2是氢,卤素,含1-3个碳原子的烷氧基,三氟甲基;及其药学上可接受的酸加成盐可用作抗抑郁药。
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