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PROCESS FOR THE PREPARATION OF 2-ŸN- (2,6-DIG-SUBSTITUTED PHENYL) -N-SUBSTITUTED AMINO-IMIDAZOLINE (2) DERIVATIVES OR THE ACID ADDITION SALTS THEREOF AND METHOD FOR PREPARING A PHARMACEUTICAL PREPARATELY.
PROCESS FOR THE PREPARATION OF 2-ŸN- (2,6-DIG-SUBSTITUTED PHENYL) -N-SUBSTITUTED AMINO-IMIDAZOLINE (2) DERIVATIVES OR THE ACID ADDITION SALTS THEREOF AND METHOD FOR PREPARING A PHARMACEUTICAL PREPARATELY.
1279543 Analgesic &c compositions BOEHRINGER INGELHEIM GmbH 18 Nov 1970 [19 Nov 1969] 54833/70 Heading A5B [Also in Division C2] Pharmaceutical compositions having analgesic activity comprise, as active ingredient, a 2-(N-phenyl-N-cycloalkyl-amino) - imidazoline- (2) of the general formula: wherein each of R 1 , R 2 and R 3 is a hydrogen, fluorine, chlorine or bromine atom or a trifluoromethyl, cyano, C 1-3 alkyl or C 1-3 alkoxy group and n is 1, 2 or 3, or a physiologically compatible acid addition salt thereof, in association with a pharmaceutical carrier or excipient and optionally a further physiologically active ingredient, e.g. a sedative, antihypertonic, tranquillizer, hypnotic or pain-killing agent and may be administered orally, enterally or parenterally as granules, tablets, coated tablets, capsules, syrups, emulsions, suspensions, drops or suppositories.
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