Process for Preparation of 2- (N-benzyl-N-methyl-ami no-ethylmethyl-2,6-dimethyl-4- (m-nitrophenyl) -1,4-dihidropiridi-na-3,5-dicarboxylate

摘要

Procedure for the synthesis of 2 - (n-benzyl-n - metilaminoetilmetil - 2,6 Dimethyl 4 - (M - nitrofenil) - 1,4 - dihydropyridine - 3.5 - dicarboxilato.Involves the reaction of N - methyl - N - bencilacion 2-aminoethanol with Benzyl Chloride in Basic Medium.Followed by the Esterification reaction of dicetena Aminoalcohol formed in the presence of acetate anhydride and cyclization reaction of dihydropyridine acetylacetic Ester by Treatment of the N - methyl - N - Benzyl - 2-aminoethanol obtained with M - nitrobenzaldehido and methyl ester of acid Aminocrotonico.