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Method for producing medicinal preparations for the treatment of carcinomas

机译:生产用于治疗癌症的药物制剂的方法

摘要

Method for producing medicinal preparations for the treatment of carcinomas. As starting material using carcinoma cells can be recovered in a conventional manner, and incubate Cells Grown in a Nutrient Growth Medium.It is subjected to a Plurality of certain portions of the Crop to the action of a Plurality of cytostatic agents, select the agent presents a visible morphological deterioration.The remaining portion of the Crop treated with the agent, preferably built up over a period of Six to twelve hours at a temperature of approximately 37 C, such that approximately 30 to 70 per 100 of these cells remain intact under microscopic examination and Program At present, weakened.These cells are washed with a weakened physiologically acceptable solution to eliminate cytostatic agents. Cells that have been weakened in the desired degree are centrifuged at approximately 800 to 1000 RPM for ten minutes and suspended Fluid preferably in A physiologically acceptable.The concentration of the cells resulting in Pharmaceutical preparations, posts for Administration after dilution, it is preferably approximately 10 cells per milliliter.
机译:生产用于治疗癌症的药物制剂的方法。由于可以以常规方式回收使用癌细胞的原材料,并在营养生长培养基中培养生长的细胞,因此需要对作物的某些部分进行复数处理,以使多种细胞抑制因子共同作用,然后选择存在的细胞因子用该试剂处理过的农作物的剩余部分,最好在约37°C的温度下在六到十二小时内积累起来,这样每100个这些细胞中约有30-70个在显微镜下保持完整检查和程序目前已经弱化。这些细胞用生理上可接受的弱化溶液洗涤以消除细胞生长抑制因子。将弱化至所需程度的细胞以约800-1000 RPM的速度离心十分钟,然后将液体悬浮于生理学上可接受的A溶液中。药物制剂,稀释后给药后的细胞浓度优选约为10每毫升细胞。

著录项

  • 公开/公告号ES8200228A1

    专利类型

  • 公开/公告日1982-01-16

    原文格式PDF

  • 申请/专利权人 LIMBURG HANS;

    申请/专利号ES19800491356

  • 发明设计人

    申请日1980-05-09

  • 分类号A61K45/05;

  • 国家 ES

  • 入库时间 2022-08-22 13:21:02

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