Oral composition for the treatment of gingivitis and periodontitis and process to improve the oral hygiene, process for treating gingivitis.Process for controlling gingivitis and process to reduce the count of gram negative bacterial microganismos anaerobios

摘要

An oral composition for treating gingivitis and periodontitis comprising an oral vehicle and an effective amount of the water insoluble antigingivitis agent, imidazoyl-1-(p- chlorophenoxy)-3,3-dimethyl 2- butanone (also known as Climbazole) solubilized in a nonionic compound containing a mixture of hydrophobic and hydrophilic groups of sufficient length to effect solubilization in an aqueous vehicle, in the weight ratio of 1:1 to 25:1 and preferably 3:1 to 25:1 solubilizer:imidazoyl compound, said agent being selectively effective against the gram negative anaerobic micro-organisms associated with periodontitis.