HYBRIDOMA FOR PRODUCING MONOCLONAL ANTIBODY TO HUMAN PERIPHERAL T CELLS AND THYMOCYTES;ANTIBODY;THERAPEUTIC COMPOSITIONS AND DIAGNOSTIC METHODS

摘要

Hybrid cell line for production of monoclonal antibody to an antigen found on essentially all normal human T cells and on approximately 95% of normal human thymocytes. The hybrid is formed by fusing splenocytes from immunized CAF1 mice with P3X63Ag8U1 myeloma cells. Diagnostic and therapeutic uses of the monoclonal antibody are also disclosed.