7 (Alpha) - alkyl - 17 (alpha) - pregn - 4 - s - 21.17 - carbonyl lactones and - 21 - carbonsaeuresalze as well as processes for their preparation and pharmaceutical preparations, various

摘要

7 alpha -substituted-17 alpha -pregn-4-ene-21, 17-carbolactones and -21-carboxylic acid salts of formula I. CHEM wherein C1@@@C2 is a C-C single or C=C double bond, CHEM R is a saturated or unsaturated, straight-chain or branched aliphatic radical of 1-6 carbon atoms, optionally substituted by a chlorine atom or a hydroxy group, and CHEM wherein M is an alkali metal, (e.g., Na, K), preferably potassium exhibit a strong antialdosterone effect and only a very slight antiandrogenic side effect.