首页> 外国专利> PHARMACEUTICAL PREPARATIONS CONTAINING FLAVENE OR THIOFLAVENE DERIVATIVES,THE USE THEREOF,NOVEL FLAVENES AND THIOFLAVENES,AND PROCESS FOR THEIR MANUFACTURE

PHARMACEUTICAL PREPARATIONS CONTAINING FLAVENE OR THIOFLAVENE DERIVATIVES,THE USE THEREOF,NOVEL FLAVENES AND THIOFLAVENES,AND PROCESS FOR THEIR MANUFACTURE

机译:包含黄酮或硫代黄酮衍生物,其用途,新型黄酮和硫代黄酮的药物制剂及其制造工艺

摘要

The invention relates to pharmaceutical preparations containing compound of Formula I CHEM in which X1 and X2, independently of each other, represent hydrogen, halogen, unsubstituted or substituted amino or a quaternary ammonium sa etherified or esterified hydroxy; free, etherified, esterified or oxidized mercapto; nitro; functionally modified formyl; free or functionally modified carboxyl; acyl; an unsubstituted or substituted hydrocarbon radical, or an unsubstituted or substituted heterocyclic radical; with the proviso that at least one of the radicals X1 and X2 is bonded by a carbon atom to the ring system and with the proviso that X1 and X2 cannot be together halogen and formyl; in which Y represents oxygen, sulfur, sulfinyl or sulfonyl but must be sulfur, sulfinyl or sulfonyl, if X1 is hydrogen and X2 is formyl; and the rings A and B are each unsubstituted or substituted; or pharmaceutically acceptable salts of such compounds that contain a salt-forming group, and to novel compounds of Formula I. The compounds are useful e.g. for the treatment of diseases of the respiratory tract and of liver diseases. They are prepared by methods known per se.
机译:本发明涉及含有式I化合物的化学制剂,其中X 1和X 2彼此独立地代表氢,卤素,未取代或取代的氨基或季铵盐;醚化或酯化的羟基;游离,醚化,酯化或氧化的巯基;硝基功能改性的甲酰基;游离或功能改性的羧基;酰基未取代或取代的烃基,或未取代或取代的杂环基;前提是基团X1和X2中的至少一个通过碳原子键合到环系统上,并且前提是X1和X2不能一起是卤素和甲酰基;其中,如果X 1为氢,X 2为甲酰基,则Y代表氧,硫,亚磺酰基或磺酰基,但必须为硫,亚磺酰基或磺酰基;环A和B各自未被取代或被取代;这些化合物或含有成盐基团的化合物的可药用盐,以及对于式I的新化合物。用于治疗呼吸道疾病和肝脏疾病。它们通过本身已知的方法制备。

著录项

  • 公开/公告号IL72776D0

    专利类型

  • 公开/公告日1984-11-30

    原文格式PDF

  • 申请/专利权人 ZYMA SA;

    申请/专利号IL19840072776

  • 发明设计人

    申请日1984-08-27

  • 分类号C07D;

  • 国家 IL

  • 入库时间 2022-08-22 08:15:17

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