PROPENYLAMINE, METHOD OF ADMINISTRATION, ROUTE(S) OF ADMINISTRATION, AND ROUTE(S) OF ADMINISTRATION

摘要

A compound of the formula: IMAGE I wherein the double bond is in the trans configuration and R1 is a radical of formula IIa, IMAGE IIa R2, R3, R5, R7 and R8 are each hydrogen, R4 is methyl, and R6 is a radical of formula IIIa -C 3BOND C-R11 IIIa where R11 is n-butyl, tertiary butyl or phenyl or a chemotherapeutically acceptable acid addition salt thereof; processes for their production, their use as pharmaceuticals and pharmaceutical compositions containing them.