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Methods to produce secropin and other heterologous polypeptides in bacterial host using araB promoter and replicating media, genetic formations and bacteria usable in the methods
Methods to produce secropin and other heterologous polypeptides in bacterial host using araB promoter and replicating media, genetic formations and bacteria usable in the methods
A polynucleotide molecule expressible in a given host comprising the sequence of the araB promoter operably linked to a gene which is heterologous to said host. The heterologous gene codes for a peptide that is biologically active. The invention also relates to a genetic construct which comprises a first genetic sequence coding for cecropin operably linked to a second genetic sequence coding for a polypeptide which is capable of suppressing the bactericidal effect of the resulting fusion protein towards an otherwise cecropin sensitive bacterium.
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