TUMOR IMAGING WITH RADIOLABELED MONOCLONAL ANTIBODIES

摘要

ABSTRACTDescribed herein are monoclonal antibodies to tumorassociated antigens to which are bound a metallic radionuclide,either directly or by means of a chelating agent such as di-ethylenetriaminepentaacetic acid (DTPA) conjugated to theantibody. When parenterally administered to a subject, thelabeled monoclonal antibody localizes in the tumor and can bedetected by photoscanning to detect emitted radiation.