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摘要

PCT No. PCT/GB85/00588 Sec. 371 Date Aug. 18, 1986 Sec. 102(e) Date Aug. 18, 1986 PCT Filed Dec. 16, 1985 PCT Pub. No. WO86/03749 PCT Pub. Date Jul. 3, 1986.A method for preparing a stable aerosol formulation of beclomethasone dipropionate in which the steroid is contacted with an alcohol containing 1 to 5 carbon atoms to form a crystalline solvate therewith, the crystalline material so formed being reduced to a particle size below 10 microns and thereafter dispersed in a composition comprising chlorofluorocarbon propellents.