首页> 外国专利> CARRIER FOR IMMOBILIZING PHYSIOLOGICALLY ACTIVE MATERIAL AND SELECTIVE ADSORBENT, SELECTIVE ELECTRODE AND ANALYTICAL COLUMN USING SAID CARRIER

CARRIER FOR IMMOBILIZING PHYSIOLOGICALLY ACTIVE MATERIAL AND SELECTIVE ADSORBENT, SELECTIVE ELECTRODE AND ANALYTICAL COLUMN USING SAID CARRIER

机译:用所述载体固定生理活性物质和选择性吸附剂,选择性电极和分析柱的载体

摘要

PURPOSE:To obtain a carrier of less nonspecific adsorption by using a base material coated with a copolymer prepd. by copolymerizing monomers of specific structures as a carrier for immobilizing physiologically active materials. CONSTITUTION:The base material coated with the copolymer consisting essentially of the monomer of hydrophilic acrylate or the like of the general formula CH2=C(R1)CO2R2OR3 (where R1=H, CH3 groups, R2=a lower alkyl group, a hydroxyl group, etc., R3=H, an alkyl group of 1-3 carbon numbers), and copolymerized with the unsatd. carboxylic acid of the general formula CH2= C(R1)CO2H or the unsatd. amine of the general formula CH2=C(R1)CO2R2 NHR3 (where R1, R3 are the similar to the above, R2=a bivalent alkylene group of 2-3 carbon numbers) is used as a carrier for immobilizing physiologically active materials. Since this carrier has less nonspecific adsorption, it is usable for clinical purpose.
机译:目的:通过使用涂覆有共聚物制备物的基材来获得非特异性吸附较少的载体。通过共聚合特定结构的单体作为载体来固定生理活性物质。组成:涂有共聚物的基材,该共聚物主要由通式为CH2 = C(R1)CO2R2OR3的亲水性丙烯酸酯等单体组成(其中R1 = H,CH3,R2 =低级烷基,羟基R3 = H,碳原子数为1〜3的烷基)与不饱和基团共聚。通式CH2的羧酸= C(R1)CO2H或未饱和。通式CH 2 = C(R 1)CO 2 R 2 NHR 3(其中R 1,R 3与上述相似,R 2 = 2-3个碳数的二价亚烷基)的胺用作固定生理活性材料的载体。由于该载体具有较少的非特异性吸附,因此可用于临床目的。

著录项

  • 公开/公告号JPS6155415B2

    专利类型

  • 公开/公告日1986-11-27

    原文格式PDF

  • 申请/专利权人 KURARAY CO;

    申请/专利号JP19810036293

  • 申请日1981-03-12

  • 分类号B01J20/281;A61K35/00;A61K35/14;A61K38/00;A61K38/16;A61K38/46;A61K39/00;A61M1/36;B01J20/22;B01J20/26;B01J20/28;B01J20/285;C07K16/00;C07K17/08;C12N11/00;C12N11/08;C12Q1/00;G01N30/88;G01N33/53;G01N33/545;

  • 国家 JP

  • 入库时间 2022-08-22 07:21:54

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