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PROCESS FOR PRODUCING GANGLYOSIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AS ACTIVE AGENTS
PROCESS FOR PRODUCING GANGLYOSIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AS ACTIVE AGENTS
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机译:制备包含它们的活性成分的党参苷衍生物和药物组合物的方法
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摘要
The invention relates to a method for preparing inner ester ganglioside derivates which comprises:… (a) dissolving a ganglioside or a mixture of gangliosides obtained from a mammal in a non-aqueous organic solvent;… (b) converting the carboxylate groups in the gangliosides to carboxyl groups or a salt thereof by means of ion exchange; and… (c) reacting the resultant ganglioside or mixture of gangliosides with a lactonization reagent to form at least one lactonic bond in said inner ester ganglioside derivatives.
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