AROMATIC BENZAMIDO COMPOUNDS, A METHOD FOR THEIR¹PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE¹AND IN COSMETICS

摘要

Aromatic benzamido compounds which have the formula: …IMAGE… in which:… R1 denotes -CH2OH, -CHOHCH3 or -COR5,… R5 denoting a hydrogen atom, a lower alkyl radical, the radical -OR6 or …IMAGE… R6 denoting a hydrogen atom, a lower alkyl radical or a mono- or polyhydroxyalkyl radical, r' and r'' denoting a hydrogen atom, a lower alkyl radical, a mono- or polyhydroxyalkyl radical, an optionally substituted aryl or benzyl radical, an amino acid or amino sugar residue or, taken together, form a heterocyclic ring,… R2 denotes an alpha , alpha -disubstituted alkyl radical containing from 4 to 12 carbon atoms or a mono- or polycyclic cycloalkyl radical containing from 5 to 12 carbon atoms, whose linking carbon is quaternary,… R3 denotes a hydrogen atom or an alkyl radical containing from 1 to 10 carbon atoms, and… R4 denotes a hydrogen atom, a lower alkyl radical or a hydroxyl radical, and the salts of the said aromatic benzamido derivatives of formula (I) when R6 denotes a hydrogen atom. …??These compounds find application in human and veterinary medicine and in cosmetics.