IMMUNOGEN ISOLATED WITH MOLLUSCS ITS PREPARATION METHOD REAGENTS FOR DIAGNOSING HUMAN BILHARZIOSES VACCINES AGAINST SCHISTOSOMIASES IMMUNOGENICITY

摘要

Glycoprotein extracted from molluscs, especially from Megathura crenulata, namely haemocyanin, which exhibits the same antigenic properties as the antigen 38 KD isolated from the surface of schistosomule of S. mansoni; its oligosaccharide epitope. Serum protecting against infections by S. mansoni, originating from a mammal immunised with the abovementioned mollusc haemocyanin or its oligosaccharide epitope. Immunogenic composition containing the said glycoprotein or its oligosaccharide epitope and its applications as a diagnostic reagent, vaccine against bilharziosis, immunising agent, and the like.