2 - / 4 - / (4,4 - dialchil - 2.6 - piperidindion - 1 -) - butylated / 1 - piperazinil / pirimidine activity selective for anxiety, process for their preparation and pharmaceutical preparations which contain

摘要

1-[4-(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]piperazines with 2-pyrimidyl substituents in the 4- position have been synthesized and demonstrate useful anxiolytic properties. The compound 4,4-dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,6-piperidi nedione, which has selective anxiolytic activity, constitutes the preferred embodiment of the invention.