首页> 外国专利> 文献详情

NOVEL LINGNAN DERIVATIVE AND ANTIULCERATIVE CONTAINING THE SAME AS ACTIVE INGREDIENT

机译:包含相同活性成分的新型岭南衍生物和止痛药

摘要

NEW MATERIAL:A lignan derivative of the formula (R1 is OH, R2 is methyl or incorporate R1 to form methylene or R1 is methyl and R2 is H). EXAMPLE:Isoschizandrin. USE:Medicine, antiulcerative. It is used to treat gastric and duodenal ulcers. PREPARATION:Dried fruits of Schizandra chinensis Baill are subjected to extraction with lower hydrocarbon such as petroleum ether at moderate temperatures. The solvent is removed from the extract and the residue is suspended in water, subjected to steam distillation to remove the essential oil. The remaining non- essential oil fraction is subjected to repeated silica-gel chromatography for purification. The resultant fraction is chromatographed with a silica-gel thin layer, eluted with a solvent such as methanol and irradiated with an ultraviolet ray of 2536Angstrom wavelength to give the compound of the formula where R1 is hydroxy and R2 is methyl.
机译:新材料:式的木脂素衍生物(R1为OH,R2为甲基或并入R1形成亚甲基或R1为甲基,R2为H)。例子:异五味子。用途:医学,抗溃疡药。它用于治疗胃和十二指肠溃疡。制备:五味子干果实在中等温度下用低级烃如石油醚萃取。从提取物中除去溶剂,并将残余物悬浮在水中,进行蒸汽蒸馏以除去精油。剩余的非精油级分经过重复硅胶色谱法纯化。所得的级分用硅胶薄层色谱法纯化,用诸如甲醇的溶剂洗脱,并用2536埃波长的紫外线照射,得到下式的化合物,其中R 1为羟基,R 2为甲基。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

联系方式:18141920177 (微信同号)

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号