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Amino substituted thienothiopyran derivatives, composition containing them, and method of using them to stimulate presynaptic dopamine receptors
Amino substituted thienothiopyran derivatives, composition containing them, and method of using them to stimulate presynaptic dopamine receptors
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机译:氨基取代的噻吩并噻喃衍生物,包含它们的组合物以及使用它们刺激突触前多巴胺受体的方法
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摘要
Disclosed are compounds of the formula IMAGE (I) wherein A represents the divalent radical -S-CR4=CR5- in which R4 and R5 independently represent hydrogen or lower alkyl; R1 represents hydrogen, lower alkyl or aryl-lower alkyl; R2 represents hydrogen, lower alkyl or aryl-lower alkyl; or R1 and R2 combined represent alkylene of 4 to 6 carbon atoms; R3 represents hydrogen or lower alkyl; an S-oxide thereof; or a pharmaceutically acceptable salt thereof; which are useful as presynaptic dopamine receptor agonists for the treatment of central nervous system disorders; processes for preparing same; and pharmaceutical compositions comprising said compounds.
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