apoAI-CIII-AIV, apoAII apoB, apoCI, and LDL receptor polymorphisms for genetic fingerprinting and predictive of atherosclerosis

摘要

The invention offers a method of genetic analysis which is potentially an early detection method for atherosclerosis. The method comprises detecting the presence or absence of polymorphic states correlated with this disease which are proximal to the apolipoprotein AI-CIII-AIV gene complex, or to the apoAII, apoB, apoCI or, LDL-R genes. Individuals with particular polymorphic sites are likely to experience severe atherosclerotic symptomologies.