ABSOLUTE CONFIGURATION ENANTIOMERS OF AMINO-3 QUINUCLIDINE AMIDE DERIVATIVES, PROCESS FOR PREPARING THEM AND THEIR THERAPEUTIC APPLICATION

摘要

ENANTIOMER OF ABSOLUTE CONFIGURATION S OF FORMULA: BR/ (CF DRAWING IN BOPI) BR/ OR X O OR S. AR REPRESENTS A PHENYL CORE SUBSTITUTED BY ONE, TWO OR THREE ALKOXY GROUPS IN C-C; A PHENYL CORE SUBSTITUTED IN POSITION 2 BY A CH GROUP AND IN POSITION 5 BY A HALOGEN ATOM OR A LOWER ALKYLCARBONYL GROUP; A PHENYL CORE SUBSTITUTED IN POSITION 2 BY OCH, IN POSITION 4 BY NH OR ALKYLCARBONYL -NH- AND IN POSITION 5 BY A HALOGEN; A GROUP (FLUORO-3 METHOXY-2) PHENYL; A PYRIMIDYNYL-5 GROUP SUBSTITUTED IN POSITION 2 BY NH AND IN POSITION 4 BY ALKOXY OR PHENYLOXY. /P P THESE COMPOUNDS ARE USEFUL AS DRUGS WITH GASTROCINTIC AND ANTIEMETIC ACTIVITY.