QUATERNARY SALT OF N,N3-DI-(BETA-BROMPROPIONYL)- N1,N2-DISPIROTRIPIPERAZINIUM, MANUFACTURE AND ANTITUMORAL MEDICINE COMPOSITION

摘要

A pharmaceutical composition intended for the treatment of an acute leukemia which comprises, as the active principle, N,N3-di-( beta -bromopropionyl)-N1,N2-dispirotripiperazinium dichloride and a pharmaceutically acceptable vehicle therefor. The active principle is used as a lyophilized powder. As the vehicle use is made of an isotonic solution of sodium chloride or distilled water. The content of the active principle in the pharmaceutical composition for injections is 2 to 5% by weight.