HUMAN GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR-LIKE POLYPEPTIDES AND PROCESSES FOR PRODUCING THEM IN HIGH YIELDS IN MICROBIAL CELLS.

摘要

polypeptides similar to the stimulation of granulocyte macrophage colonies, with a specific activity of at least 1 x 108 units / mg and their manufacturing processes.dna sequences, recombinant dna molecules, and hosts transformed by microbial, producing in large quantities of polypeptides similar to the granulocyte colony stimulating factor of human macrophage, and processes for the manufacture of these polypeptides.the polypeptides of the invention are similar to granulocyte colony stimulating factor on macrophage can be used for the treatment of cancer patients to regenerate leukocytes after treatment with radiation or chemotherapy, and to increase the count of white blood cells to reduce the likelihood of a bacterial, viral infection.fungi and parasites, especially in patients with compromised immunity, such as those who are living with hiv / aids.