THYMIDINE KINASE-NEGATIVE TEMPERATURE RESISTANT BOVINE HERPESVIRUS-1 MUTANT AS A VACCINE AGAINST INFECTIOUS BOVINE RHINOTRACHEITIS

摘要

Described are thymidine kinase negative temperature resistant mutants of bovine herpesvirus effective in inducing resistance to infectious bovine rhinotracheitis, methods for their production, methods for maintaining them in viable form, and methods for administering them to animals in immunologically effective doses to induce reistance to infectious bovine rhinotracheitis.