PURPOSE:To obtain an adsorbent capable of specifically adsorbing human beta2- microglobulin casing carpal tunnel syndrome by immobilizing a substance having specific bonding property to human beta2-microglobulin on a carrier. CONSTITUTION:A substance having specific bonding property to human beta2- microglobulin, e.g., antibody against human beta2-microglobulin, its H-chain, L- chain, Fab fragment or F(ab')2 fragment is immobilized on a carrier preferably having a rejection critical molecular weight of protein of 108-109 or having an average pore diameter of 50-1,000nm by activated ester process, condensation process, carrier crosslinking process, etc. The amount of the substance immobilized on the carrier is preferably 1X10-8-1X10-6mol/g-carrier.
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