Process for the preparation of 1-fluorinated vitamin D compounds, or 1-fluoro-5,6-trans vitamin D compounds, or 1-fluoro-3,5-cyclovitamin D compounds

摘要

Fluorine-substituted vitamin D compounds, methods for preparation of such compounds and fluorinated intermediate compounds used in such methods are disclosed. The fluorine-substituted vitamin D compounds are characterized by vitamin D-like activity in stimulating intestinal calcium transport and bone mobilization and in promoting the calcification of rachitic bone.