Lactam derivatives, processes for the preparation thereof, pharmaceutical compositions comprising the same, and the use of such derivatives for the manufacture of a medicament having valuable therapeutic properties

摘要

There are disclosed a lactam derivative of the formula:wherein R¹ is a substituted or unsubstituted phenyl group; R² is a substituted or unsubstituted phenyl group, a cycloalkyl group or a nitrogen-containing 6-membered heterocyclic group; Z is oxygen atom or sulfur atom; and n is an integer of 2 or 3, and a salt thereof, and a preparation thereof.;The above lactam derivative is novel and useful as a pharmaceutical compound. Accordingly, pharmaceutical preparations are also provided, together with the use of such derivatives for the manufacture of a medicament having valuable therapeutic properties.