Antibodies against fibrin, immunogen used in their preparation, process for determining fibrin and pharmaceutical preparation based on the antibodies

摘要

Antibodies are provided, which are directed against a sequence of amino acids corresponding to amino acids from the sequence 111-207, in particular 148-161, of the Aα-chain of fibrinogen. These novel antibodies react specifically with fibrin, both type I and type II, and not with fibrinogen. They are effective in detecting, prevent­ing and treating blood clot formation.