Optically active isomer of cloperastine possessing antitussive activity, a process for its preparation and pharmaceutical compositions which contain it

摘要

The present invention relates to the optical isomers of cloperastine, a compound of formula: Because of the presence of the asymmetric carbon atom marked with the asterisk, the compound (I) exists in its dextrorotatory and levorotatory isomer forms.;The invention provides a process for the optical resolution of raceme DL-cloperastine and pharmaceutical compositions containing L-cloperastine.