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antihelmintische macrocyclische lactones and their fermentative manufacture.
antihelmintische macrocyclische lactones and their fermentative manufacture.
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机译:抗蠕虫大环内酯及其发酵生产。
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摘要
A novel microorganism ATCC-53110 is formed by the protoplast fusion of strains of Streptomyces avermitilis and Streptomyces hygroscopicus. A novel macrolide is isolated from the fermentation broth of this microorganism. The structure of the novel compounds isolated from the microorganism is presented based upon analytical studies. The compounds are highly potent antiparasitic, insecticidal, and anthelmintic agents, and may be made into suitable compositions for pharmaceutical, veterinary and agricultural use. The compounds have the formula: CHEM in which R1, R2 and R3 are defined as follows: TABLE f
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