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DETERMINATION OF ANTI-P FALCIPARUM SPOROZOITE ANTIBODIES IN HUMAN BLOOD.
DETERMINATION OF ANTI-P FALCIPARUM SPOROZOITE ANTIBODIES IN HUMAN BLOOD.
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机译:人体血液中抗-P恶性疟原虫抗体的测定。
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摘要
An immunoenzimatic method is disclosed for the detection and the measurement of anti-P. falciparum sporzoite antibodies in human blood and/or in its derivatives, which operates with a synthetic antigen-enzyme conjugate capable of forming with the antisporozoite antibodies a stable antibody-synthetic antigen-enzyme complex, and one or more proteins absorbed and/or covalently linked to a solid support, which eagerly bind the antisporozoite antibody of said complex. The method, thanks to its simpleness, specificity and rapidity, is particularly useful in epidemiologic investigations into malaria and into the efficacy of an antimalarial vaccine.
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