PURPOSE:To obtain a cerebral nerve function improver useful for dysmnesia, senile dementia, etc., having 5-HT2 antagonism, comprising a specific diphenylethylpiperazine derivative or a salt thereof as an active ingredient. CONSTITUTION:A cerebral nerve function improver containing a compound shown by formula I (Ar and Ar' are lower alkyl or lower alkoxy; R is H, lower alkyl, lower alkoxy, etc.; A is 1-6C lower alkylene; n is 0-1) or a salt thereof. A new compound shown by formula II (R1 and R2 are H or F; R3 is H, lower alkyl, lower alkoxy, halogen or lower alkylenedioxy) among the compounds shown by formula I is excellent as an anti-dementia agent even with a small amount. The compound shown by formula I can be orally or parenterally administered, a dose is usually 1-1,000mg daily and administered once-several times daily.
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