ORALLY ADMINISTRABLE NOVEL GALENUNU MEDICINE OF SULPIRIDE

摘要

Orally administrable compositions containing sulpiride in microgranules formed by a neutral grain material and having an outer layer of a microporous polymer. The use of such compositions, which are made by projecting a solution of sulpiride onto the neutral grains and then applying the polymer, makes it possible to achieve absorption of sulpiride double that which is obtained with conventional capsules, while retaining a slightly greater period of action and considerably reducing the differences in absorption from one subject to another. The rate of liberation of sulpiride in artificial gastric and intestinal media is specified.