(BFGF) BASIC FIBROBLAST GROWTH FACTOR DERIVATIVES PRODUCED BY SITE DIRECTED MUTAGENESIS OF HUMAN OR BOVINE DNA

摘要

Pentapeptides and derivatives thereof, including derivatives having one or more additional amino acids inserted in the sequence and/or added at the C- and N-termini, have been found to possess good activity in the inhibition of stem cell proliferation. In addition groups of novel peptides are disclosed, having improved and/or specifically directed inhibitory actions.