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METHOD FOR PREPARING A LIPOPROTEIN MODIFIED BY THE INCORPORATION OF A LIPOPHILIC ACTIVE SUBSTANCE

机译:脂质体活性物质的结合修饰的脂质体的制备方法

摘要

A process for preparing a lipoprotein modified by the incorporation of at least one lipophilic active substance other than a triglyceride, characterized in that it incorporates said active substance in an emulsion of a lipid phase in an aqueous continuous phase, that to the emulsion was added with stirring a starting lipoprotein and at least one lipid transfer protein, we incubated the mixture, and which is isolated according to known methods wherein the lipoprotein active substance is incorporated; lipoprotein thus obtained modified, and pharmaceutical or cosmetic composition containing such a modified lipoprotein.
机译:一种通过掺入至少一种除甘油三酸酯以外的亲脂性活性物质而改性的脂蛋白的方法,其特征在于,将所述活性物质掺入在水连续相的脂质相的乳状液中,并向其中加入搅拌起始脂蛋白和至少一种脂转移蛋白,我们孵育混合物,并根据已知方法分离,其中掺入脂蛋白活性物质;如此获得的脂蛋白被修饰,以及包含这种修饰的脂蛋白的药物或化妆品组合物。

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