The new 4 1 rank displacement (the 4 imidazolyl) application to piperidine and the production manner and the clinical medicine

摘要

The compounds correspond to the general formula (* CHEMICAL STRUCTURE *) in which R1 represents a hydrogen atom or a group -COR2, in which R2 represents a benzene ring, cyclopentylmethyl, cyclohexylmethyl, cyclopentylethyl or cyclohexylethyl groups or cyclopentylamine, cyclohexylamine or phenylamine, chlorophenylamine or dichlorophenylamine groups; R represents a hydrogen atom or a group COR3, in which R3 represents an aliphatic group, a cyclane or benzene ring-system, a group a group (CH2)mR4, a group -CH=CHR8 or a secondary amine group -NH(CH2)nRg; R also represents a hydroxyalkenyl group: (* CHEMICAL STRUCTURE *)