PURPOSE: To obtain the subject simple pharmaceutical preparation, comprising a therapeutically effective amount of rifaximin together with a vaginally applicable carrier, effective against vaginal infection, especially bacterial vaginosis without any adverse effects. CONSTITUTION: This pharmaceutical preparation is obtained by coating a preparation composed of a suspension containing (A) 2-8wt.% micronized rifaximin having =100m particle diameter, (B) 2-6wt.% thickening substance such as cetyl stearyl alcohol or a hydrogenated castor oil and (C) 86-96wt.% oily substance such as a mineral oil or a liquid paraffin according to the U.S. Pharmacopoeia with an epoxy phenolic resin, including the resultant preparation in a canister, closed with a valve made of polyethylene and made of aluminum and further introducing a propellant gas in an amount of 60-100wt.% based on the suspension through the valve thereinto. Furthermore, the content of the rifaximin is 50-500mg.
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