首页> 外国专利> PROCEEDING FOR OBTAINING MIXTURES FROM GANGLIOSIDES FOR TREATMENT OF CHARACTER AND PSYCHO-ORGANIC DISORDERS.

PROCEEDING FOR OBTAINING MIXTURES FROM GANGLIOSIDES FOR TREATMENT OF CHARACTER AND PSYCHO-ORGANIC DISORDERS.

机译:从甘柳甙中获取混合物以治疗性状和心理有机疾病的方法。

摘要

(a) Chlorinated or aromatic alkanes and inert organic solvents were extracted from homogenous nerve tissues in different stages, then filtrate was filtered and diluted with water to dehydrate the formed non saline alcohol phase; (b) gangliosis at this stage was retained by using anonico exchange material, Then wash clothes with a cane (c) The glycerol retained in the mixture of water alkane solvent and non-polar organic solvent was recovered in alkaline medium;(d) The solvent was distilled, and the residue was extracted from the solvent mixed with water alkane and low polar organic solvent, and the material was purified by adsorption chromatography in silica gel column; (e) Dilute with the above solvent mixture and the increasing polar mixture, and collect the separation containing gangliosis; (f) evaporate the solvent medium by recovering the residue from the separated gangliosis.
机译:(a)在不同阶段从均质神经组织中提取氯化或芳香族烷烃和惰性有机溶剂,然后过滤滤液并用水稀释以使形成的非生理盐水相脱水; (b)在这一阶段使用阴离子交换材料保留神经节,然后用拐杖洗衣服(c)在碱性介质中回收保留在水烷烃溶剂和非极性有机溶剂混合物中的甘油;(d)蒸馏除去溶剂,从与水烷烃和低极性有机溶剂混合的溶剂中提取残余物,并通过硅胶柱上的吸附色谱法纯化该物质。 (e)用上述溶剂混合物和增加的极性混合物稀释,并收集含有神经节的分离物; (f)通过从分离的神经节中回收残留物来蒸发溶剂介质。

著录项

  • 公开/公告号AR241751A1

    专利类型

  • 公开/公告日1992-12-30

    原文格式PDF

  • 申请/专利权人 LABORATORIOS BETA S.A.;

    申请/专利号AR19890314371

  • 发明设计人

    申请日1989-07-12

  • 分类号A61K37/20;C07H1/08;

  • 国家 AR

  • 入库时间 2022-08-22 05:12:42

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