首页>
外国专利>
Glycolytic promoters for regulated protein expression: protease inhibitor
Glycolytic promoters for regulated protein expression: protease inhibitor
展开▼
机译:糖酵解促进蛋白表达的调控蛋白:蛋白酶抑制剂
展开▼
页面导航
摘要
著录项
相似文献
摘要
Promoters associated with expression of specific enzymes in the glycolytic pathway are used for expression of alien DNA, particularly yeast promoters known to provide high enzyme levels of enzymes in the glycolytic pathway are employed for expressing a mammalian protein, such as &agr;.sub.1 -antitrypsin. The promoters include promoters involved in expression of pyruvate kinase, triose phosphate isomerase, phosphoglucose isomerase, phosphoglycerate mutase, hexokinase 1, hexokinase 2, glucokinase, phosphofructokinase, and aldolase, as well as the glycolytic regulation gene. Particularly, the glycolytic regulation gene can be used in conjunction with promoters in the glycolytic pathway for regulated production of desired proteins.
展开▼