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Anti- shiyotsuku medicine

机译:安智四月明治闪耀

摘要

PURPOSE:An anti-shock agent for recovering abrupt reduction in blood pressure such as especially a large amount of bleeding, drug poisoning), anaphylaxis, etc., remedying effectively shock symptoms, having actions different form those of existing vasodilator, containing PGD2 or PGE1 as an active ingredient. CONSTITUTION:An anti-shock agent containing PGD2 or PGE1 as an active ingredient. PGD2 and PGE1 recover abrupt reduction in blood pressure such as a large amount of bleeding, drug poisoning, anaphylaxis, circulatory organ disorders, etc., and remedy effectively shock symptoms. Although PG compound have low solubility and are unstable, formation of inclusion compound with a cyclodextrin, preferably gamma-cyclodextrin gives powder with high stability and solubility and an anti-shock agent in a good injection state or in ampul state is prepared.
机译:用途:一种抗休克剂,用于恢复血压的突然下降,例如大量出血,药物中毒,过敏性反应等,有效纠正休克症状,其作用与现有血管扩张药不同,含有PGD2或PGE1作为有效成分。组成:一种抗震剂,含有PGD2或PGE1作为有效成分。 PGD​​2和PGE1可恢复血压的突然下降,例如大量出血,药物中毒,过敏反应,循环器官疾病等,并有效地治疗休克症状。尽管PG化合物具有低溶解度并且不稳定,但是与环糊精,优选γ-环糊精形成包合化合物使得粉末具有高稳定性和溶解性,并且制备了处于良好注射状态或安瓿状态的抗冲击剂。

著录项

  • 公开/公告号JPH0647542B2

    专利类型

  • 公开/公告日1994-06-22

    原文格式PDF

  • 申请/专利权人 リ-ドケミカル株式会社;

    申请/专利号JP19850120134

  • 发明设计人 斉藤 晴夫;森 政雄;

    申请日1985-06-03

  • 分类号A61K31/557;A61K47/40;

  • 国家 JP

  • 入库时间 2022-08-22 04:53:21

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